Italy have restored stalwarts Martin Castrogiovanni, Marco Bergamasco and fly-half Luciano Orquera to the starting line-up to play Samoa in Nelspruit this weekend.
The Europeans made seven chances for the match, with experienced centres Gonzalo Canale and Gonzalo Garcia also restored and winger Tomasso Iannone getting his third cap.
Only one uncapped player was named in the match-day 23 with hooker Andrea Manici set for his debut off the bench.
If Samoa beat Italy they will set up a likely quad series final against South Africa next weekend.
