13 February 2012 - 1:47 am NZ time
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Colin Sutherland explains what malaria is, it's evolutionary history and resistance to drugs, and how it can be halted. (12′43″)
Dallas Mildenhall from GNS uses pollen grains and spores to detect fake pharmaceuticals. (13′05″)
Dillon Mayhew explains what the abstract mathematical construct called a matroid is and why he thinks they are beautiful. (12′41″)
Peter Dearden and Rosannah McCartney are looking at how two distinct types of female honey bees can stem from one genome. (12′40″)
Every year hundreds of millions of people suffer from malaria, and millions - especially young children - die from it. Alison Ballance talks with Colin Sutherland from the London School of Hygiene and Tropical Medicine about this deadly disease, its evolutionary history - especially the evolution of drug resistance - and finds out about research into public health measures that can help halt its spread. Colin Sutherland's research areas include drug resistance, infectious disease, malaria, molecular epidemiology and parasites, and he was in New Zealand earlier this year taking part in the Bio-ed conference, held as part of the international Charles Darwin celebrations. Listen here for an Our Changing World story about avian malaria.

Pollen grains and a mite (centre) found in fake pharmaceuticals (image: Dallas Mildenhall)
Although fake pharmaceuticals are not yet a major concern in New Zealand, they are a huge problem in other parts of the world. One way to detect a non-genuine drug is by identifying fake holograms on the packaging (pdf). Last week on Our Changing World, Dallas Mildhenhall from the Institute of Geological and Nuclear Sciences explained how tiny pollen grains and spores can be used to help solve criminal cases. He has also pioneered their use in detecting fake pharmaceuticals, like anti-malarials, as a recent article in the New York Times outlined.
MatroidsMatroids are abstract objects that lie just beneath the surface of many naturally-occurring mathematical entities. In the late 1960s a catalogue of up to eight element matroids was constructed. Recently, Dillon Mayhew from Victoria University and his Australian colleague, Gordon Royle, constructed a catalogue of up to nine element matroids. In both instances, the advances would not have been possible without computers. To the right is one of Dillon Mayhew's favourite matroids.

Honey bees are useful in many ways - they pollinate our crops, and they provide us with honey. And it turns out they're also a very useful 'model' animal for genetic research, and one whose complete genome has been sequenced. Geneticist Peter Dearden (above) and PhD student Rosannah McCartney are investigating how bees can produce two distinct kinds of females - workers and queens - from a single genome. Peter Dearden is in the Laboratory for Evolution and Development, Biochemistry Department at the University of Otago, and he is also the Director of Genetics Otago, a new research group which was launched in Dunedin on 6 August.

Cells containing queen larvae, and (right) workers clustered around queen bee (all images: Laboratory for Evolution and Development)
The Galileo Lecture Series celebrates 2009 International Year of Astronomy, marking 400 years since Galileo used a telescope to view the solar system and transform our understanding of Earth's place in the Universe. All lectures are open to the public and admission is free. The Galileo Lecture Series is produced by Radio New Zealand National in partnership with the Royal Society of New Zealand, and is taking place around the country from 11-12 and 19-21 August. Email lectures@radionz.co.nz for a list of dates and locations.
Quantum nanodots; from fish to worms - volume one of New Zealand's Inventory of Biodiversity; New Zealand's venomous creatures; biowastes.
Presenters:
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Alison Ballance
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Ruth Beran
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Veronika Meduna
A mix of in depth interviews, packages and sound rich features, Our Changing World covers topics across all scientific disciplines, natural history and environmental issues, and developments in health as well as exploring the human side of science and the personalities behind it.
email: ourchangingworld@radionz.co.nz
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