Reinvestigating psychedelic drugs

From Saturday Morning, 8:15 am on 2 May 2015

the lysergic acid diethylamide LSD molecule C H N O PD via wikicommons
The lysergic acid diethylamide (LSD) molecule, C20H25N3O. Image: Ben Mills, PD

Professor David NuttDavid Nutt is the chair of DrugScience, the only completely independent, science-led drugs charity in the UK, and the Edmund J Safra Professor of Neuropsychopharmacology and Head of the Department of Neuropsychopharmacology and Molecular Imaging at Imperial College London.

Amongst other work, his team are the first in the world to scan the brains of volunteers under the influence of LSD.

The results are incomplete, but look similar but more profound than those with an earlier study of people under the influence of psilocybin ('magic mushrooms').

Unexpected and interesting results include the drug’s ability to switch off parts of the brain including some which are overactive in disorders such as obsession and depression. Dr Nutt sees potential for a one-off treatment which could have a long-term improvement in mood.

However, he says studying these drugs takes three or four times longer than a similar study of a legal drug, and costs about ten times, because of licences and regulations which need to be complied with.

“…this is the worst censorship of scientific research in the history of mankind. There is nothing comparable in the ability to stop research.” – Dr David Nutt.

There has been little scientific research on psychedelic drugs since LSD was banned in 1967. Prior to that, over 1000 studies suggested, among other things, that the use of LSD to treat alcoholism gave better results than any existing treatment.

“The drug laws exist largely as a political weapon, they don’t exist to provide health benefits, and that’s wrong.”

Professor Nutt is in favour of the decriminalisation of drugs because he thinks criminalising people for drug use does them more harm than good, leading to injustice and social unrest. Also he says the criminalisation of drugs has severely limited scientific research. He calls for evidence-based drug policy.

"Most sensible people realise the drug war is a failed war … two thirds of the American population now have access to medical marijuana, and a significant number have access to recreational marijuana, which means the American drug enforcement agency no longer controls the thinking of America, and therefore no longer has the right to control the thinking of the rest of the world, which is what it’s done up 'til now. So now there’s a real opportunity for countries that what to try something different to actually be heard, and effectively develop their own rational policy.”    

David Nutt talks to Kim Hill about his work.