Pfizer is to cut 6000 jobs worldwide - almost a fifth of its workforce - over the next five years as part of a major restructuring.
Pfizer, the world's largest drug-maker, will close eight plants and reduce operations at six other factories.
The BBC reports the changes follow its purchase of a rival company, Wyeth, last year.
The company has 78 manufacturing sites and employs about 33,000 people worldwide.
