Auckland District Health Board chairman Pat Snedden says he wanted to remain in the role but was told by Health Minister Tony Ryall just over a month ago that he wasn't going to be reappointed.
Mr Snedden, who was a Labour Party appointment and has had several high-profile roles in the health sector over the past decade, announced his resignation on Thursday.
Mr Snedden says he asked Mr Ryall for his intentions regarding the position and was told a new chair will be named.
Mr Snedden says he would have liked another three years in the role but understands the prerogative of all new Governments to install the people they want in key positions.
While he says he would have liked more focus on Maori and Pacific health issues, but says there was no falling out between himself and Mr Ryall. He says every minister has their own particular style and Mr Ryall's is very direct.
Mr Ryall says it's not unusual for Governments to refresh board leadership.
The Labour Party says arrogant leadership by the minister is causing an exodus of experience in the sector.