Italian rugby's tour to Australia and New Zealand has been hit by the withdrawals of experienced prop Martin Castrogiovanni, halfback Simon Picone and fullback Andrea Marcato.
The Italian Rugby Federation says Castrogiovanni and Marcato are injured while Picone misses out due to "personal reasons".
The squad is already without fullback Andrea Masi and hooker Carlo Festuccia as the Metro Racing pair are from the Abruzzo region that was badly hit by an earthquake in April. They have decided to stay with their families.
The trio have been replaced by Viadana prop Ignacio Rouyet, halfback Kristopher Burton of Prato and the uncapped Parma halfback Tito Tebaldi.
The squad will meet in Rome on June the 1st before leaving for Melbourne two days later.