Swede Robert Karlsson, the 2008 European number one, has withdrawn from next week's US Open because of an eye infection.
Karlsson, who tied for fourth in last year's U.S. Open at Torrey Pines outside San Diego, has been struggling with depth perception in his left eye, according to his manager.
The 39-year-old has been replaced in the Open field at Bethpage Black in Farmingdale, New York by American Andrew Svoboda.
A nine-times winner on the European Tour and the first Swedish player to clinch the circuit's order of merit title, Karlsson pulled out of last week's Wales Open because of an inner ear infection.
Karlsson's consistency set him apart from the rest on the 2008 European Tour as he piled up eight top-three finishes, including victories at the Mercedes-Benz Championship and the Alfred Dunhill Links Championship.
He flourished in the majors, sharing eighth place at last year's Masters, tying for fourth at the U.S. Open and ending up joint seventh at the British Open.
This season, however, Karlsson has recorded only one top-10 in eight starts, a tie for fourth at the Dubai Desert Classic in February.