Penrith captain Petero Civoniceva's NRL season is over and he is also out of Australia's end-of-year tour.
The Queensland Australian prop will undergo surgery to repair the tendon in his big toe this month which he ripped from the bone in the second State of Origin game.
Civoniceva had hoped the injury would have mended in time for him to make a comeback for the finals.
But his specialist, who returns from overseas next week, believes surgery is the only solution to Civoniceva's foot injury.
It's a tough blow for the lion-hearted Civoniceva who was keen to play in the inaugural Quad Series against New Zealand, Great Britain and France after being part of the Kangaroos side which lost last year's World Cup to the Kiwis.
After winning four games in a row the Panthers have slipped since the State of Origin series and sit on the edge of the top eight on 20 points equal with ninth placed Manly.