The Warriors captain will miss Saturday night's round 21 NRL match against the Panthers after being ruled out with a rib cartilage complaint.
Price hopes to be back for the home game against Gold Coast on August 9.
But prop Evarn Tuimavave is set for his 100th NRL appearance in Penrith after being side-lined for most of this season with neck and shoulder injuries.
Tuimavave's been named on the interchange bench, and with Price out, Russell Packer and Sam Rapira will be the starting props.
Other changes see centre Jerome Ropati replace Patrick Ah Van after missing last Sunday's loss to St George Illawarra with a shoulder injury and Jacob Lillyman starting in the second row with Ben Matulino going to the bench.