Burnley celebrated their first home match in the top division of English football for 33 years with a shock 1-nil victory over Premier League champions Manchester United at Turf Moor.
Robbie Blake's smart volley from outside the box in the first half gave Burnley a memorable victory after United's Michael Carrick saw his penalty well saved by Brian Jensen just before the break.
Michael Owen, partnering Wayne Rooney in a disappointing United attack, was replaced after the hour by Dimitar Berbatov but their attempts for an equaliser were stopped by an inspired Jensen.
Liverpool put an opening defeat to Tottenham Hotspur behind them with a 4-nil victory over Stoke City.
Rafa Benitez's side went ahead after just four minutes when Spanish striker Fernando Torres met Steven Gerrard's cross to score before Glen Johnson grabbed a second before the break.
Great work from captain Gerrard allowed Dutchman Dirk Kuyt to add a third on 78 minutes and David Ngog added a fourth late in the game.
Elsewhere, a Jermain Defoe hat-trick helped Spurs to a 5-1 victory at Hull City to make it two wins from two, while Birmingham City beat Portsmouth 1-nil.