The British second seed Andy Murray has suffered a shock straight sets loss to 16th seed Marin Cilic of Croatia, at the U.S. Tennis Open in New York.
Cilic reached his first grand slam quarter final with a 7-5 6-2 6-2 win.
Muray who finished runner up at last year's tournament, was foiled in his bid to become the first British man to win a Grand Slam title since Fred Perry in 1936.
Cilic will play for a semi-final berth against Argentine sixth seed Juan Martin Del Potro, who ousted Spanish 24th seed Juan Carlos Ferrero.
Murray had beaten Cilic in their three prior meetings, most recently in the fourth round of this year's French Open, but looked off-form from the start.