Stoke scored 2 goals in extra time to beat Manchester City 3-1 in an English football FA Cup fifth-round replay to reach the quarterfinals.
While Tottenham and Aston Villa made it safely into the last eight with replay victories, big-spending City's only realistic target now is finishing fourth in the Premier League, which would at least mean qualification for next season's Champions League.
City is sitting in fifth place in the league standings and has 15 points to make up on leader Chelsea.
Stoke now faces Chelsea in the last eight of football's oldest club competition as it bids to win the trophy for the first time in its history.
Roman Pavlyuchenko scored twice as eight-time FA Cup winner Tottenham thrashed Bolton 4-nil to reach the last eight, where it will visit Fulham.
Bolton aided Tottenham's cause by scoring two own goals.
Two penalties by John Carew in the last nine minutes gave Villa a 3-1 victory over cash-strapped Crystal Palace in another replay.
Villa, a seven-time FA Cup winner, will next visit second-tier Reading, which reached the quarterfinal for the first time since 1927 by winning 3-2 after extra time at West Bromwich Albion.