Wayne Rooney is a major doubt for Manchester United's Champions League clash against AC Milan.
Rooney missed United's 1-nil victory at Wolverhampton Wanderers with a knee injury which he aggravated playing the full 90 minutes for England against Egypt mid-week.
Ferguson had criticised his leading striker for playing from start to finish in England's friendly on a leg-sapping Wembley pitch, just three days after scoring the winner in the League Cup final.
United won the opening leg of their first knockout round tie 3-2 in the San Siro but the loss of Rooney for Thursday's (NZ time) match would be a blow, especially with Michael Owen ruled out for the season.
Ferguson says Dimitar Berbatov would most likely start against AC Milan.
