India's spinners wreaked havoc after captain Mahendra Singh Dhoni and Suresh Raina starred with the bat, to clinch a 126-run victory over England in the first of five one-day cricket internationals.
Ravindra Jadeja picked up three wickets with his part-time left-arm spin and off-break bowler Ravichandran Ashwin took three more as England, chasing a target of 301, were bundled out for 174 in 36.1 overs at the Rajiv Gandhi International Stadium.
After electing to bat first India were reduced to 123 for four but Dhoni (87 not out) and Raina (61) helped them rally to finish on 300 for seven.
The home team smashed 150 runs in the last 15 overs as Dhoni and Raina, who survived a close run-out decision on 16, flayed the England attack.
India, playing at home for the first time since winning the 50-over World Cup in April, failed to win a single international match on their tour of England earlier this year.
The visitors, who left out Ian Bell and selected young Jonny Bairstow instead, suffered a middle order collapse after captain Alastair Cook (60) fell to Jadeja.
Opener Cook hit seven boundaries and put on 71 for the third wicket with Jonathan Trott (26) before he holed out in the deep while trying to up the scoring rate.
The second match will be in Delhi on Monday.