Manchester United will travel to Aston Villa without striker Dimitar Berbatov as injuries continue to dog the Premier League football champions.
The Bulgarian striker has an ankle injury, while Brazilian twins Rafael and Fabio will also miss Sunday's game after limping off in Thursday's 2-1 defeat by Crystal Palace in their League Cup quarter-final.
The latest injuries come with midfielder Tom Cleverley and striker Michael Owen already sidelined for another few weeks, while midfielder Anderson has been ruled out until February with a knee injury.
The trip to Villa comes before Thursday's key Champions League match at FC Basel, where United need a draw to avoid an embarrassing group-stage exit.
Ferguson's team are second in the Premier League, trailing leaders Manchester City by five points.