Hollywood screenwriter and director Nora Ephron, who wrote such films as When Harry Met Sally and Sleepless in Seattle, has died in New York at the age of 71.
Her son says she died of complications relating to acute myeloid leukaemia.
Ms Ephron grew up in California, and started her career reporting for the New York Post.
Her 15 film credits also include You've Got Mail, Silkwood and Julie and Julia, which was her final film, in 2009.
She was nominated for an Oscar three times, but never won the award.
Ephron wrote essays for major US magazines from the late 1960s, as well as several non-fiction books, including two recent memoirs.
She was married three times, once to Carl Bernstein, the Washington Post reporter who helped uncover the Watergate scandal
Tom Hanks and When Harry Met Sally star Billy Crystal are among actors who have been paying her tribute.