A passenger jet overshot a runway in northeast China before splitting in two and bursting into flames, killing 43 people.
Chinese media reports say the Henan Airlines plane carrying 96 passengers and crew crashed in heavy fog shortly after 9.30pm on Tuesday near Yichun's Lindu airport, in Heilongjiang province.
Hua Jingwei, an Communist Party official in Yichun, told the official Xinhua news agency that 43 bodies had been recovered from the wreckage and 53 survivors taken to hospital for treatment.
State media say the plane's flight data recorder has been found.
Yichun airport is a small domestic facility which opened only last year, and is one of an increasing number of airports built in remote parts of China to help boost economic development.
China's last major civilian aircraft crash was in 2004, when a CRJ200 operated by China Eastern Airlines came down in a frozen lake in northern Inner Mongolia shortly after take-off, killing more than 50 people.