A pilot on a Continental Airlines flight from Brussels to Newark died in mid-flight on Thursday, but the plane landed safely in New Jersey under the control of two co-pilots.
The Boeing 777 had 247 passengers on board.
The plane's pilot, 60, was based in Newark and had worked for Continental for 32 years, the airline said.
Continental said in a statement that he had apparently died of natural causes.
"The crew on this flight included an additional relief pilot who took the place of the deceased pilot. The flight continued safely with two pilots at the controls," it said.