Roger Federer's bid for a seventh Wimbledon title is over after a five-set quarterfinal loss to Jo-Wilfried Tsonga.
The French 12th seed pulled off a stunning upset against the Swiss, coming from two sets down to win in five sets 3-6 6-7 6-4 6-4 6-4 in London on Wednesday.
It was the first time the No 3 seed has lost a Grand Slam match from two sets to love up.
Tsonga's semifinal opponent will be No 2 seed Novak Djokovic, who ended the adventure of 18-year-old Australian qualifier Bernard Tomic in four sets 6-2 3-6 6-3 7-5.
Defending champion Rafael Nadal booked his place in the semifinals, overcoming American 10th seed Mardy Fish 6-3 6-3 5-7 6-4.
The Spanish world No 1, who suffered an injury scare in his fourth round victory over Juan Martin Del Potro on Monday, showed no sign of discomfort as he eased past his Florida-based opponent.
British hope Andy Murray advanced to the semis with a straight-sets win over Spain's Feliciano Lopez 6-3 6-4 6-4, and will next play Nadal.
Murray has now reached seven Grand Slam semi-finals, more than any other British man.
New Zealand's Marina Erakovic and Thai partner Tamarine Tanasugarn are surprise qualifiers for the women's doubles semifinals, beating third seeds Liezel Huber and Lisa Raymond from the United States 4-6 7-6(1) 13-11 to advance to the final four.