Police in the Commonwealth of the Northern Marianas say they received a 911call from a 37-year-old female bartender around the time she disappeared.
The FBI and Department of Public Safety agents are conducting the search for Emerita Relata Romero, an employee of Godfather's Bar.
Her family members and friends joined the search that focused in the Marpi area.
The incident comes nine months after the disappearance of sisters Faloma and Maleina Luhk, a case which remains unsolved.
Romero, a Filipino, reportedly made a 911 call on Sunday morning but the phone was cut off.
Romero was reportedly last seen at about 3am that morning boarding a green or blue tinted sedan in the parking lot of Call-A-Ride Saipan in front of Musung in Garapan.