Alzheimer's disease is an incurable neurological condition that affects 35 million people worldwide. Almost 30,000 New Zealanders live with the disease, and there are predictions this figure will double over the next 15 years as we age.
But our understanding of what actually causes Alzheimer's and how it develops is still unclear. so finding a cure or a way to prevent it has been tricky.
He talks with Simon Morton about what he's learnt about the genetic basis of Alzheimer's and treatments for it from studying the brains of sufferers.