Heineken has bought a controlling stake in the owner of DB Breweries in a deal worth $US4.5 billion ($5.6 billion Singapore).
An improved bid by the Dutch brewer secured a stake of 40% held by Fraser & Neave of Singapore in Asia Pacific Breweries.
Fraser & Neave's shareholders now need to approve the sale, which was announced on Saturday.
If confirmed, the deal would give Heineken a stake of 82% in Asia Pacific Breweries, triggering an automatic takeover offer for the remaining shares of APB.
The BBC reports this would cost a further $2.5 billion Singapore.
The company will continue to be based in Singapore.