The four who died in a house fire in Mangere were children.
The Fire Service was called to the blaze in Nicola Place at 12.45am on Tuesday: 10 people were at the three-bedroom house at the time.
Two adults and two other children were taken to Middlemore Hospital.
A man, 44, and a girl, 13, are described as being in a critical condition in intensive care. Details are not available on the others.
It's believed the fire began in the kitchen.
The Fire Service says a thorough investigation will begin when the bodies have been removed.