The seeds continued to fall at the season-opening Brisbane International tennis event with German Florian Mayer toppled by former Australian Open runner-up Marcos Baghdatis.
The 71-minute upset meant world No.28 Mayer was the second seed in the men's draw, on top of five in the high-quality women's field, to be bundled out of the tournament.
The sixth seed was far from his best as Baghdatis broke him four times on Pat Rafter Arena for a 6-4 6-2 victory.
All the top four seeds received first-round byes.
World number three Andy Murray will meet local hope John Millman today to start his title defence.