The Blues have lost their third straight Super Rugby game after the Cheetahs kicked a last-minute penalty to win 25-24 in Bloemfontein on Saturday morning.
Cheetahs first five eighth Joe Pietersen booted the late penalty as the South Africans snatched the last-gasp victory at the Free State Stadium, their second win from two games this season after last weekend's bye.
The Blues led 14-12 at half-time.
Blues captain Jerome Kaino scored on his 100th Super Rugby appearance to go with tries from flanker Luke Braid and prop Charlie Faumuina.
The visitors' No.10 Ihaia West converted all three tries and added a penalty but missed a drop-goal attempt from in front of the posts after the hooter had sounded.
Springbok wing Cornal Hendricks scored two tries in the first half for the hosts with halfback Sarel Pretorius adding another.
Pietersen kicked two conversions and two penalties, including his last-minute effort after the Blues had infringed at a lineout.