Canadian Milos Raonic is the latest top ten tennis player to be hit by injury ahead of this month's US Open.
Raonic has withdrawn from the Cincinnati Open tournament due to a wrist injury.
"My wrist injury has not healed," the Canadian said in a statement posted on the tournament's Twitter feed on Tuesday. "I always play well in Cincinnati and will miss the great fans."
Ranked 10th in the world, Raonic admitted his wrist was ailing after dropping a 6-4 6-4 decision to Frenchman Adrian Mannarino last week in a second-round match at the Rogers Cup in Montreal.
Raonic, 26, has 28-11 record in 2017.
He is the fifth notable player with injury concerns ahead of the US Open joining Switzerland's Roger Federer (back), Scotland's Andy Murray (hip),Croatia's Marin Cilic (adductor) and Japan's Kei Nishikori (wrist).
In addition, Serbia's Novak Djokovic is done for the season with an elbow injury.