Andy Roddick's hopes of an extended Wimbledon warm-up have suffered a blow, beaten in the third round of the Queen's Club event.
The 2003 US Open champion and three-time Wimbledon finalist lost 6-4 7-6 to Israel's Dudi Sela.
World number one and French Open champion Rafael Nadal needed three sets to beat the unseeded Denis Istomin of Uzbekistan.
