The United States Anti-Doping Agency has filed formal doping charges against Lance Armstrong that, if proven, would strip him of his seven Tour de France titles.
A three-member review panel evaluated evidence gathered by the agency and a reply from Armstrong before unanimously voting to turn the accusations into formal charges.
The ABC reports the next step in the process will be a hearing before an arbitration panel.
The panel's verdict could be appealed and the matter could be pushed to the Court of Arbitration for Sport for a final resolution.
The US Doping Agency claims it has witnesses that Armstrong and five former cycling team associates engaged in a doping conspiracy from 1998-2011.
It also says his blood samples from 2009 and 2010 are fully consistent with doping.