Holders Chelsea or Manchester United will face Manchester City in the FA Cup semi-finals and Wigan Athletic will play Championship Millwall or Blackburn Rovers following today's draw.
Manchester United raced into an early 2-nil lead over Chelsea who fought back to draw 2-all at Old Trafford in their quarter-final, forcing a replay at Stamford Bridge.
Their last cup meeting there produced a nine-goal thriller with Chelsea beating United 5-4 in a League Cup match in October, three days after United won a league game 3-2 at Stamford Bridge.
Premier League champions Manchester City, who won the FA Cup two years ago after beating United in the semi-finals, romped into the last four with a 5-nil win over Championship strugglers Barnsley yesterday.
Wigan Athletic reached the semis for the first time in their 81-year history when they won 3-nil at Everton yesterday and they will play Blackburn or Millwall who drew nil-all in south London.
The semi-finals will take place at Wembley on April 13th and 14th.