New South Wales rugby league coach Laurie Daley's dumped both last year's halves for next week's State of Origin opener.
The Sydney Roosters duo of Mitchell Pearce and James Maloney have been jettisoned in favour of the Bulldogs pairing of Josh Reynolds and debutant Trent Hodkinson.
Pearce's premiership-winning Roosters team-mate Daniel Tupou will also make his Origin debut on the wing at Suncorp Stadium next Wednesday night.
Tony Williams returns to the Origin arena after missing last year's series through poor form.
With Greg Bird suspended and Boyd Cordner injured, Beau Scott and Ryan Hoffman fill the Blues' second row.
New South Wales: Jarryd Hayne, Brett Morris, Josh Morris, Michael Jennings, Daniel Tupou, Josh Reynolds, Trent Hodkinson, Aaron Woods, Robbie Farah, James Tamou, Ryan Hoffman, Beau Scott, Paul Gallen (captain)
Reserves: Anthony Watmough, Tony Williams, Trent Merrin, Luke Lewis