Aid agencies have called on the United Nations Security Council to reach an agreement with the Syrian authorities on humanitarian access.
Groups including Save the Children and the Norwegian Refugee Council have warned in a letter that thousands of people need help urgently, the BBC reports.
The UN Security Council has been unable to stop the violence in Syria, but in a letter addressed to council members the leaders of aid agencies said innocent Syrians should not be held hostage to the ongoing deadlock at the political level.
The group warned that the violence engulfing entire cities and towns had displaced hundreds of thousands of people - some for the third or fourth time - and called on the Security Council to secure urgent funding.
So far, a UN appeal for $US189 million to aid those inside Syria has raised just 20% of the money needed.
Fighting continues in neighbouring Lebanon
Street battles between Sunni Muslims and Alawites in Lebanon's northern town of Tripoli have continued for a second night, killing seven people and wounding more than 70.
The army has intervened, but has failed to stop the fighting on Tuesday.
Old rivalry between the two groups has been fuelled by conflicting loyalties in the conflict across the border in Syria.
Syrian president Bashar al-Assad, an Alawite, is battling largely Sunni opposition fighters.
Lebanese Prime Minister Najib Mikati, a Sunni, appealed to both sides to end the what he called the absurd battle rocking Tripoli - a city of nearly 200,000 people and the country's second-largest.
